Royal Air Force Typhoon FGR4s have operated alongside France's air force in a coordinated attack targeting an underground arms cache in Syria used by the Daesh militant organization, as stated by the UK Ministry of Defence.
The location, pinpointed through reconnaissance, was thought to be storing arms and explosives, the release indicated, and was situated in mountainous terrain just to the north of Palmyra in central Syria.
"Our aircraft utilized laser-guided Paveway IV weapons to strike a series of entry passages providing entry to the depot... early reports indicate the strike was effective," the MoD said.
There was no sign of any harm to civilians in the strike late on Saturday and all the aircraft returned to base without incident, the MoD added.
The British jets were backed up by a Voyager tanker plane.
Daesh - referred to as ISIS - established extremist governance over parts of Iraq and Syria prior to its 2019 collapse.
"This strike underscores British leadership, and determination to work closely with our allies, to eliminate any revival of the terrorist group and their violent and radical beliefs in the region," Britain's Defence Chief the Defence Secretary remarked.
RAF aircraft have performed patrols over Syrian airspace to "deter any attempted comeback" of Islamic State following its military defeat at the climactic battle in Baghuz in 2019, the MoD reported.
"I must thank the personnel of our armed forces who took part in this mission for their professionalism and their bravery," the Defence Secretary commented. "Including them were a great many UK service members deployed over the holidays. This action, to remove dangerous terrorists who pose a risk to our way of life, demonstrates how British military are always on standby, continuously, protecting the UK within its borders and influential overseas."
During December, the United States armed forces conducted what it described as a "massive strike" against IS targets in Syria, after an attack resulted in the deaths of two US troops and a civilian linguist in the Palmyra area.
The UN estimates IS still maintains roughly 5-7 thousand fighters in Syria and Iraq.